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Tag: 02-NATSARS(COV2)ST

Mitochondrial DNA deletions are associated with non-B DNA conformations

Posted on April 18, 2021 by Jordan

To interrogate mtDNA-CN as a potential determinant of human diseases, we performed extensive genetic investigations in up to 395,781 participants from the UKBiobank study. We first developed and validated a novel method for biobank-scale mtDNA-CN investigations that leverages SNP array intensities, called “AutoMitoC”. Various analyses were then conducted to build on previous publications regarding the… Continue reading

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