Skip to content

MITOchondrial DYNamics variation portal

The ACO2 gene homepage – Variation OPA1 mutation database

Menu
  • Home
  • Polyclonal
  • Isotype
  • Medium
  • Distributors
  • Serum
  • Vector
  • antigen
  • Assay
  • Contact Us
Menu

Mitochondrial DNA molecules during embryogenesis

We developed a novel method to estimate mtDNA-CN from genetic array data, “AutoMitoC”, and applied it to the UKBiobank study. Extensive genetic invesal key insights regarding mtDNA-CN.

Insert the swab through the nostril entry and then slowly
move along the bottom of the nasal cavity (Move gently to
avoid traumatic bleeding).

First, several novel common and rare genetic determinants of mtDNA-CN were identified, totalling 73 loci. Second, these loci were enriched for mitochondrial processes related to dNTP metabolism and the replication, packaging, and maintenance of m; common variation within known mtDNA depletion genes in regulating mtDNA-CN in the general population. Fourth, we found that rare variants in SAMHD1 not only affect mtDNA-CN levels but also confer risk to cancer.

Finally, we provided the first Men Randomization evidence implicating low mtDNA-CN as a causative risk factor for dementia.

Recent Posts

  • Compare Pcr lab reagents for research
  • Compare Pcr lab reagents for research
  • recombinant Lab Reagents for Research
  • Comparison of seven commercial SARS-CoV-2 rapid point-of-care antigen tests
  • Performance characteristics of five antigen-detecting rapid diagnostic test

Recent Comments

    Categories

    • antigen
    • Assay
    • Enzyme
    • ethidium
    • Isotype
    • Medium
    • Polyclonal
    • Recombinant
    • rna
    • Uncategorized
    January 2023
    M T W T F S S
     1
    2345678
    9101112131415
    16171819202122
    23242526272829
    3031  
    « Dec    

    Categories

    • antigen
    • Assay
    • Enzyme
    • ethidium
    • Isotype
    • Medium
    • Polyclonal
    • Recombinant
    • rna
    • Uncategorized

    Recent Posts

    • Compare Pcr lab reagents for research
    • Compare Pcr lab reagents for research
    • recombinant Lab Reagents for Research
    • Comparison of seven commercial SARS-CoV-2 rapid point-of-care antigen tests
    • Performance characteristics of five antigen-detecting rapid diagnostic test
    © 2023 MITOchondrial DYNamics variation portal | Powered by Superbs Personal Blog theme