Mitochondrial network of human fibroblast in vivo observed by epifluorescence microscopy.
The acquisition plans in the Z axis, followed by an image processing algorithm deconvolution (Huygens ®), allows 3D reconstruction (Imaris ®). The mitochondrial network is marked in red (TMRM probe ®), the nucleus in blue and green mitochondrial DNA (probe Pico Green ®).
Cover photo of Medecine Sciences (Paris, Oct. 2010), by Mitolab.